

Eriodictyon (Yerba Santa, Holyherb)
INCI: Butylene Glycol, Eriodictyon Californicum (Holyherb) Flower/Leaf/Stem Extract
Genoprotective plant extract for anti-aging & UV protection
Eriodictyon is a genus of plants in the subfamily of waterleaf plants. The botanical active ingredient derived from the species Eriodictyon californicum is an extract that is highly valued in modern skincare, particularly for its DNA-protective, antioxidant, and photoprotective effects. Eriodictyon—also known as Yerba Santa or Holyherb—supports the skin’s natural repair mechanisms and helps counteract light-induced skin aging.
What is Eriodictyon?
Eriodictyon californicum is an evergreen plant native to the dry, mountainous regions of Central America. Indigenous peoples of the Americas valued it for its medicinal and spiritual significance; Spanish missionaries called it “Yerba Santa”—the “Holy Herb.”
The leaves are coated with a protective resin and contain high levels of flavonoids, particularly eriodictyol and homoeriodictyol. These phytochemicals are responsible for the plant’s antioxidant and skin-protective properties.
The Effects of Holyherb in Skincare
1. Protection of cellular DNA against UV damage
UV radiation, environmental pollution, and stress cause DNA damage in skin cells. This impairs cell renewal and promotes premature skin aging.
In studies on human keratinocytes, Eriodictyon extract demonstrated a dose-dependent reduction in DNA fragmentation following UVB irradiation.
This means that the active ingredient supports the skin cells’ natural repair processes and helps reduce light-induced cell damage.
2. Support for the DNA repair protein p53
The p53 protein, also known as the “Guardian of the Genome,” plays a central role in repairing damaged DNA.
Holyherb acts as a p53 modulator and thus supports:
- the activation of cellular protective mechanisms
- the regulation of stress responses
- the regeneration of the skin from within
In addition, a reduction in cellular stress markers was observed under UV stress.
3. Antioxidant & Photoprotective Effect
The flavonoids and tannins contained in Holyherb have the following effects:
- antioxidant
- free-radical-scavenging
- photoprotective
- soothing
As a result, the extract protects the skin from oxidative stress and prevents photoaging (light-induced skin aging).
For which skin types is Holyherb suitable?
Eriodictyon (Holyherb) is particularly suitable for:
- mature skin
- sun-damaged skin
- stressed, dull skin
- urban skin exposed to high environmental stress
- sensitive skin experiencing oxidative stress
Holyherb in cosmetic formulations
Typical applications for this active ingredient include:
- Anti-aging facial care
- Day creams with UV protection
- Sunscreen products
- After-sun products
- Regenerating serums
When combined with hyaluronic acid, niacinamide, ceramides, or panthenol, ectoine can further enhance its stabilizing effect.
Why is Holyherb a modern anti-aging ingredient?
Modern anti-aging approaches focus not only on wrinkles, but also on cellular protection and DNA integrity. Eriodictyon offers:
- ✓ Protection against UV-induced DNA damage
- ✓ Support for natural repair mechanisms
- ✓ Antioxidant protection against free radicals
- ✓ Promotion of skin regeneration
This makes Eriodictyon an innovative active ingredient for high-quality skincare products focused on scientifically proven cell protection and sustainable regeneration.
Conclusion
Eriodictyon (Eriodictyon californicum) is a multifunctional plant extract with genoprotective, antioxidant, and photoprotective effects. It protects the skin from environmentally induced aging, supports DNA repair, and strengthens the skin’s natural regenerative capacity—ideal for modern anti-aging and UV protection formulations.




